No matter what kind of medicine you take, whether OTC (over-the-counter) or prescription, it is destined to take a trip through your kidneys. Taking a drug the wrong way or in excessive amounts can damage these vital, bean-shaped organs and lead to serious complications. In the worst-case scenario, it could necessitate a kidney transplant.“Compared with 30 years ago, patients today…have a higher incidence of diabetes and cardiovascular disease, take multiple medications, and are exposed to more diagnostic and therapeutic procedures with the potential to harm kidney function,” according to Cynthia A. Naughton, Pharm D, senior associate dean and associate professor in the department of pharmacy practice at North Dakota State University. All of these factors are associated with an elevated risk of kidney damage. An estimated 20% of cases of acute kidney failure are due to medications. The technical term for this scenario is “nephrotoxicity,” which is growing more common as the aging population grows, along with rates of various diseases. A dosage of 1 g of valacyclovir 3 times per day (TID) for 7 days has already been shown to be superior to an oral dosage of 800 mg acyclovir 5 times per day for 7 days in immunocompetent individuals. The objective of this study was to assess the safety and efficacy of an oral dosage of valacyclovir, 1 g TID versus 2 g TID, for the treatment of herpes zoster in immunocompromised patients ⩾18 years of age. The oral dosage schedule of 2 g of valacyclovir TID reaches acyclovir plasma levels similar to those achieved with intravenous acyclovir therapy given to immunocompromised patients (10 mg/kg every 8 h for 7 days). In this double-blind study, 87 immunocompromised patients with clinical evidence of localized herpes zoster were randomized to receive oral valacyclovir therapy for 7 days, either 1 g TID or 2 g TID, within 72 h after onset of zoster rash. Patients were seen and assessed for cutaneous healing, zoster-associated pain (ZAP), and/or zoster-associated abnormal sensations (ZAAS), up to 24 weeks. Participants in both arms of the study demonstrated similar median times to full crusting of the rash (8 days), and both dosages were safe and effective therapies for reduction of ZAP and ZAAS in the immunocompromised patient population Trials registration Clinical identifier: NCT00006131 Herpes zoster, or shingles, is a common disease caused by a reactivation of the varicella-zoster virus (VZV). Subsequent to primary VZV infection (i.e., chickenpox), the virus lies latent in the dorsal root ganglia, and reactivation can occur at any age [1, 2]. Compare xanax and valium Buy ventolin solution The latest Tweets from MSU @michiganstateu. The official Twitter account for Michigan State University. #SpartansWill. East Lansing, MI USA Detailed drug Information for Valtrex. Includes common brand names, drug descriptions, warnings, side effects and dosing information. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Mayo Clinic does not. Less common. Constipation; diarrhea. Valacyclovir is used to treat herpes zoster (shingles) and genital herpes. It does not cure herpes infections but decreases pain and itching, helps sores to heal, and prevents new ones from forming. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. It is usually taken every 8 hours (three times a day) for 7 days to treat shingles. To treat genital herpes it is usually taken twice a day for 5 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor. Use this medication as soon as possible after symptoms appear. Continue to take valacyclovir even if you feel well. Please complete all the fields below to send the bad drug report. Each field is required to be completed in order to send. The submission of this form does not form an attorney client relationship. An attorney client relationship will only be formed after the execution and return of a retainer agreement. Valtrex may decrease kidney function, especially when combined with other drugs. When used along with other kidney damaging medications, Valtrex can be extremely dangerous. The following may be harmful to the kidneys: Valtrex is an FDA pregnancy Category B drug. Does valtrex cause constipation Valtrex Side Effects in Detail -, Valtrex Advanced Patient Information - Levitra how to use Tap along the timeline to move to different parts of the audio file. ChemoExperts Tips. Bortezomib can cause reactivation of herpes HSV- herpes simplex virus or. RVd or VRd treatment for Multiple Myeloma ChemoExperts. Valacyclovir Oral Route Side Effects - Mayo Clinic. Valacyclovir 101 How it Works, Side Effects & More - Hims. Vous désirez joindre l'équipe de Solaris Québec? Contactez un représentant dès maintenant par courriel ou bien par téléphone. Medical Editor John P. Cunha, DO, FACOEP. Our Valtrex Side Effects Drug Center provides a comprehensive view of available drug information on the. It is used to treat shingles caused by herpes zoster, genital herpes, and cold sores. and ask your doctor or pharmacist to explain any part you do not understand. stomach pain; joint pain; headache; constipation; vomiting; cold symptoms.