This article was co-authored by our trained team of editors and researchers who validated it for accuracy and comprehensiveness. wiki How's Content Management Team carefully monitors the work from our editorial staff to ensure that each article meets our high How marks an article as reader-approved once it receives enough positive feedback. This article has over 651,351 views, and 98% of readers who voted found it helpful. It also received 35 testimonials from readers, earning it our reader-approved status. Retin-A is a topical prescription medication made from an acidic form of vitamin A. Although the medication was originally designed to treat acne, dermatologists found that Retin-A creams are also extremely effective in combating signs of aging - including wrinkles, dark spots and sagging. This article will tell you all you need to know about using Retin-A to reduce wrinkles, allowing you to turn back the clock! 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